@prefix rdf:	<http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix ns1:	<http://purl.obolibrary.org/obo/> .
@prefix owl:	<http://www.w3.org/2002/07/owl#> .
ns1:RO_0002630	rdf:type	owl:ObjectProperty .
@prefix rdfs:	<http://www.w3.org/2000/01/rdf-schema#> .
ns1:RO_0002630	rdfs:subPropertyOf	ns1:RO_0002212 ,
		ns1:RO_0002578 ;
	rdfs:label	"directly negatively regulates" ;
	ns1:IAO_0000115	"Process(P1) directly negatively regulates process(P2) iff: P1 negatively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2).  For example, if protein A has protein binding activity(P1) that targets protein B and this binding  negatively regulates the kinase activity (P2) of protein B then P1 directly negatively regulates P2." .
@prefix ns4:	<http://purl.obolibrary.org/obo/ro/docs/> .
ns1:RO_0002630	ns1:IAO_0000119	ns4:causal-relations ;
	ns1:IAO_0000589	"directly negatively regulates (process to process)" ;
	ns1:RO_0004050	ns1:RO_0002578 .